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A Meta-Analysis of the Effects of Exercise Programs on Glucose and Lipid Metabolism and Cardiac Function in Patients with Type¥± Diabetes Mellitus

Journal of Korean Academy of Nursing 2005³â 35±Ç 3È£ p.546 ~ 554
KMID : 0806120050350030546
À¯Áö¼ö/ Yoo JS
À̼÷Á¤/Lee SJ

Abstract

Purpose: This study was a systematic review and meta-analysis of the effects of exercise programs in patients with type ¥± diabetes mellitus.

Method: Two investigators systematically searched and reviewed English articles from PUBMED from 1988 to 2004, selecting randomized controlled trials on structured exercise programs for DM patients. Out of 87 studies identified, a meta analysis was done for eleven studies which satisfied inclusion criteria and focused on glycemic indices, lipid indices, and cardiac function indices.

Results: The means and standard deviations were compared for experimental groups that received exercise-only or exercise and diet programs and control groups that received no intervention or only diet education. The groups were considered homogeneous as the p value of the Q score in each variable group was over 0.05. The experimental groups demonstrated a moderate positive effect on HbA1c and VO2max (d=0.55 & 0.5), and a small positive effect on fasting blood glucose and cholesterol (d=0.38 & 0.27) compared to the control groups. HDL and LDL cholesterol levels, however, showed a very low positive effect (d=0.11 & 0.12) in the experimental groups. Aerobic exercise was more beneficial than resistance exercise on HbA1c (d=0.59 vs 0.28) in the groups.

Conclusions: Regular exercise has a positive effect on HbA1c, fasting blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, and VO2max in Type 2 diabetic patients.
KeyWords
Meta-Analysis, Exercise, Diabetes mellitus, Glucolysis, Lipolysis, ´ç´¢º´, ¿îµ¿, ¸ÞŸºÐ¼®, ´ç´ë»ç, ÁöÁú´ë»ç, ½ÉÆó±â´É
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